MTA-KE Mycotoxins in the Food Chain Research Group
The research group carries out interdisciplinary research in the field of mycotoxins contaminating the food chain, based on a broad and modern methodological toolbar, to get new data for the scientifically based risk assessment. We investigate the effect of mycotoxins on the composition of the gut microbiota, the potential protective effect of pro- and prebiotics, and the toxin metabolising ability of the gut microbes in different animal species. Research is performed on the effect of these toxins and their metabolites with respect to the relationship between lipidperoxidation, glutathione system, membrane lipid composition and certain intrinsic enzyme activities. We aim to investigate multitoxic effects, the time and dose dependent geno-, cyto- and reproductive toxicity of more mycotoxins and their metabolites, in different combinations. The metabolism, accumulation and elimination of fumonisin and the toxicity of its derivatives is specifically addressed. These results provide data for the determination of tolerable limit values, which are needed in feed and food safety, animal and human prevention.